That might not be to uncomfortable to shoot actually... I shot one of those "normal" derringers in 9mm and it felt like getting punched in the hand! Neat design.
I can't begin to say how much I would not want/own that pistol.
With all the good, tiny, semi-auto pistols out there, that you don't have to grab a very short barrel to load (friend of mine blew off part of his hand when the derringer he was working on -- gunsmith -- went off), why have a gun which requires you to put your hand near (and possibly over) the muzzle when loading it?
I'd take any of the .380 semi-autos first.
But, different opinions is why they make different guns.
have you seen the price on those? too salty for me......if i wanted to spend that kind of money id prolly get a Bond Arms and buy an extra barrel for it.