HB209, set for committee vote April 19, 2022, would modify/restrict state pre-emption.
https://www.legis.la.gov/legis/BillInfo.aspx?s=22RS&b=HB209&sbi=y
Remember though, those local laws which predate state preemption are still subject to the state constitution (even though some local officials act as if their laws are exempt.) If Opelousas declined prosecution in their most recent case, this could be why. A prosecution would probably result...